Articles from Bioxodes

Gosselies, Belgium, 10 December 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, has raised €5.5 million in a Series A extension funding round, enabling the company to continue preparations to launch a potentially registrational Phase 2b trial of its lead candidate BIOX-101 to treat intracerebral hemorrhage (ICH) in 2027. Newton Biocapital, a specialist life science venture capital firm focusing on early-stage companies in Europe and Japan, entered as a new investor, together with other new and existing shareholders, bringing the total Series A financing to about €17.5 million.

Gosselies, Belgium, 14 November 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, has held a webcast on the breakthrough potential of its lead candidate BIOX101 to treat intracerebral hemorrhage (ICH) and discussed the data with Prof Dr Robin Lemmens, KU Leuven, the Principal Investigator of its Phase 2a BIRCH clinical trial. Prof Lemmens, a world-renowned stroke expert and head of the stroke unit at the University Hospital Leuven, underscored the urgent need to address the large unmet medical need in intracerebral hemorrhage, and provided his insights from the successful Phase 2a clinical study with BIOX-101. Bioxodes CEO Marc Dechamps presented the company’s strategy in bringing BIOX-101 to market, possibly as early as late 2030.

Gosselies, Belgium, 7 October 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, today announced the appointment of Philippe Monteyne, MD, PhD, as chairman of its Board of Directors. Dr. Monteyne, a neurologist, has an extensive and successful track record as a life sciences investor and as a pharmaceutical executive, having held a range of senior industry positions and overseen the development and launch of multiple new medicines.

Gosselies, Belgium, 11 September 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, today announces encouraging second interim results from the BIRCH Phase 2a clinical trial of its lead asset, BIOX-101, to treat intracerebral hemorrhage (ICH). The results confirm and expand upon the positive findings of the first set of interim results, announced in April. The new data show that all patients treated with BIOX-101 experienced a reduction in hematoma. This finding was further supported by biomarker measurements, all of which trended in support of the clinical observations. The Data Monitoring Committee in its recommendation unanimously endorsed proceeding to a Phase 2b or Phase 3 efficacy trial.

Gosselies, Belgium, 24 April 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, today announces promising interim results from the BIRCH Phase 2a clinical trial of its lead asset, BIOX-101, to treat intracerebral hemorrhagic stroke (ICH). Interim analysis from the first 16 patients in the standard-of-care controlled, randomized trial showed that primary safety and secondary efficacy endpoints were met. The Data Monitoring Committee (DMC) identified no safety concerns related to changes in ICH volumes, serious adverse events, neurological outcomes, or mortality.

Gosselies (Belgium), 5 March 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, has received Orphan Drug Designation (ODD) for its first-in-class BIOX-101 therapeutic candidate to treat intracerebral hemorrhagic stroke (ICH) from both the U.S. Food and Drug Administration (FDA) and the E.U.’s European Medicines Agency (EMA).

Gosselies (Belgium), 12 February 2025 (08:30 am CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, has raised €2.7 million from existing investors in an extension of its Series A funding round, now totaling about €15 million. The proceeds will allow the company to deliver full results from BIRCH, its Phase 2a trial of BIOX-101 to treat intracerebral hemorrhage (ICH), an orphan disease with no currently approved therapeutic intervention, and prepare for the launch of a potentially registrational Phase 2b trial of BIOX-101 for ICH.

Gosselies (Belgium), 19 December 2024 (08:30 CET) – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, has enrolled the first 16 of 32 patients in the open-label, randomized and controlled Phase 2a clinical trial of its lead asset BIOX-101 in patients with intracerebral hemorrhagic stroke (ICH). Treatment of the first 16 patients will trigger an interim analysis, according to the trial protocol. Data of these patients will be available for investors under condition of confidentiality, as is already the case with currently available patient data. BIOX-101 is a proprietary novel therapeutic candidate, a peptide which Bioxodes has developed from a protein discovered in tick saliva.

Gosselies (Belgium), August 21, 2024 – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies to prevent and treat thrombotic and inflammatory diseases, announces today that the DMC reviewed the data from the first 8 patients in a planned review of the ongoing BIRCH Phase 2a trial of BIOX-101 to prevent secondary damage after intracerebral hemorrhagic stroke (ICH).

 First-in-class drug candidate evaluated in first eight patients

Gosselies (Belgium), May 16, 2024 – Bioxodes SA, a clinical stage biopharmaceutical company developing novel therapies for the prevention and treatment of thrombotic and inflammatory diseases, announces today it has received a notice from the European Patent Office of its intention to grant a patent for the lead asset of Bioxodes, BIOX-101 (Ir-CPI), further broadening the candidate therapy’s protection in thromboinflammation, and adding to the company’s strong portfolio of intellectual property rights, which include a related approval in Australia, dating from June 2022, and a pending patent grant from Russia’s Center for Intellectual Property Rights.